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About Human Growth Hormone
Synthetic Growth hormone (rHGH) is called somatropin (British: somatrophin). hGH refers to human growth hormone and is an abbreviation for human GH (Somatotropin) extracted from human pituitary glands. In 1985, biosynthetic human growth hormone replaced pituitary-derived HGH for therapeutic use in the U.S. and elsewhere. Biosynthetic human growth hormone, also referred to as recombinant growth hormone, is also called somatropin and abbreviated as rhGH. Since the mid-1990s the abbreviation HGH has begun to carry paradoxical connotations, and now rarely refers to real GH used for indicated purposes. See articles on GH treatment and hGH quackery for fuller discussions of GH therapy and the HGH issue.
What is Somatropin?
Somatotropin, also commonly referred to as human growth hormone (HGH), is a hormone that is produced in the human body and excreted into the blood by the somatotrope cells of the anterior pituitary gland. It is a single-chain protein that is composed of 191 amino acids with a molecular weight of approximately 22,000 Daltons.
GH secretion has many direct and indirect effects on the human body. First, GH stimulates the liver's production of insulin-like growth factor (IGH-1). Because GH stimulates the liver's production of IGF-1, the effects of both GH and IGF-1 are listed below.
Synthetic version of Human Growth Hormone is called Somatropin (191 amino acid sequence growth hormone). It is identical to human body's own GH. However that is not the case for Somatrem (192 amino acid sequence growth hormone). But we will talk about that later.
Direct and Indirect Effects of Somatotropin on the Human Body:
Stimulates division and multiplication of the chondrocytes of cartilage
Increases both calcium retention and the mineralization of bones
Stimulates cell growth in every organ of a human body
Increases metabolism
Repairs damaged cells
Induces protein synthesis
Decreases protein degradation
Stimulates the immune system
Promotes lipolysis
Increases glucose transport
In the human body, somatotropin is at its highest levels in children and during puberty, stimulating the growth of the body during those ages. After puberty, the level of growth hormone secretion declines and continues to do so as a person ages.
Growth hormone deficiency (GHD) is a disease in which a person's pancreas fails to produce an adequate amount of normal endogenous growth hormone. In children, this results in short stature and growth failure. In adults, GHD causes deficiencies of strength, energy, and bone mass.
GHD can be treated in both children and adults with somatropin, also known as synthetic human growth hormone (HGH). However, to treat conditions of height, a child must be treated before the growth plates (epiphyses) at the ends of long bones have fully matured and closed.
Healthy adults most commonly use Human Growth Hormone for Anti Aging, Body Building and Fat Loss purposes.
Common Uses of Human Growth Hormone:
Growth Hormone Deficiency
Treatment for small gestational age (SGA) and intrauterine growth retardation (IUGR)
Idiopathic Short Stature
AIDS Wasting and Cachexia
Short Stature Caused by Turner's Syndrome
Short Stature Caused by Prader-Willi Syndrome
Growth Problems Caused by Short Bowel Syndrome
Improper Growth in Children with Renal Disease
Body Building Enhancement Drug
Weight Loss Drug
Anti-Aging Drug
Treatment for Children with Rheumatoid Arthritis
Osteoporosis Treatment
Treatment for Children with X-Linked Hypophosphatemic Rickets (XLH)